The Effects of Hyperacute Serum on the Elements of the Human Subchondral Bone Marrow Niche

Figure 2

Time-course effect of serum supplements on MSCs. (a) Subconfluent MSCs were cultured in DMEM in the absence of supplement (serum free (white bar)), or supplemented with FCS (light-gray bar), FCS + bFGF (dark-gray bar), PRP (black bar), or HAS (red bar). (b) Cell morphology of MSCs using phase-contrast microscopy. Confidence interval -value: 0.0001 to 0.001, extremely significant.

(a)

(b)