Research Article

Human Umbilical Cord MSC-Derived Exosomes Suppress the Development of CCl4-Induced Liver Injury through Antioxidant Effect

Figure 2

hucMSC-Ex reduced oxidative stress in mouse liver tumor. (a, b) The levels of 8-OHdG, SOX9, and collagen in mouse livers were measured by immunohistochemistry or Sirius red staining in liver tumor treated with PBS or hucMSC-Ex. Original magnification 200x. Compared with the PBS group, hucMSC-Ex significantly reduced production of oxidative stress marker 8-OHdG, SOX9 expression, and collagen deposition in liver tumor (; , ).
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