Therapeutic Effect of Human Umbilical Cord Mesenchymal Stem Cells at Various Passages on Acute Liver Failure in Rats

<div>Histopathological recovery of D-GaIN/LPS-induced ALF transplanted with hUCMSCs at 24 h, 48 h, and 72 h. (a) H&amp;E staining showed that there were massive necrosis and hepatic lobule damage in the NS group. In contrast, hepatocyte necrosis was suppressed in both P5 hUC-MSCs group and P10 hUC-MSCs group after transplantation. hUC-MSCs treatment also reduces the number of inflammatory infiltration. The black circles represent the hepatocyte necrosis and severe inflammatory cell infiltration. Bar = 200 <i>μ</i>m. (b) Histopathological grading of necrosis and inflammation of the liver sections. 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Stem Cells International

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Figure 3

Figure 3: Therapeutic Effect of Human Umbilical Cord Mesenchymal Stem Cells at Various Passages on Acute Liver Failure in Rats 