Genome-Wide DNA Methylation Analysis during Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells

<div>The gene expressions of BMP1, PAX1, and RUNX3 along with the osteogenic differentiation in BMSCs. (a) RT-q-PCR results showed that the expression of BMP1 was decreased after osteogenic induction. (b, c) RT-q-PCR results showed that the expression of PAX1 and RUNX3 was increased after osteogenic induction. GAPDH was used as an internal control. One-way ANOVA test was performed to determine statistical significance. 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Stem Cells International

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Figure 5

Figure 5: Genome-Wide DNA Methylation Analysis during Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells 