Emerging Role of Histone Acetyltransferase in Stem Cells and Cancer

Table 3

Involvement of HAT in stem cells.

HAT	Target	Effect in normal stem cells	Ref
CBP		Maintenance of self-renewal hematopoietic stem cells	[61]
p300	OCT4, SOX2, KLF4	Stem cell reprogramming	[54]
		Proliferation and odontogenic differentiation of human dental pulp cells	[56]
		Self-renewal and pluripotency maintenance in ESCs	[57]
		Proper hematopoietic differentiation	[61]
GCN5	Myc	Early reprogramming initiation in mouse PSC	[62]
	NF-κB	Osteogenic commitment of mesenchymal stem cells	[64]
	DKK1	Osteogenic differentiation of periodontal ligament stem cells	[65]
pCAF	BMPs	Osteogenic differentiation of mesenchymal stem cells	[66]
MOF	NANOG, OCT4, SOX2	Maintenance of ESC self-renewal and pluripotency	[68]
		Stem cell reprogramming	[69]
Tip60		ESC differentiation into mesoderm and endoderm lineages	[71]
MOZ	p16(INK4a)	Maintenance of proliferation in hematopoietic and neural stem cells	[72]