Evaluation of Chitosan Hydrogel for Sustained Delivery of VEGF for Odontogenic Differentiation of Dental Pulp Stem Cells

Figure 4

The CS/β-GP hydrogel promoted the proliferation of DPSCs and constantly released VEGF. The results of CCK-8 assay showed the promoted proliferation of DPSCs plated on the CS/β-GP hydrogel and in hydrogel leachates (a, b). DPSCs cultured in base culture medium (NC) without hydrogels or hydrogel leachates were as controls. ELISA assay showed the cumulative release profiles of VEGF/CS/β-GP hydrogel (c). ELISA assay showed the release amount of VEGF from hydrogel every day (d).

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(b)

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