Development of Bifunctional Three-Dimensional Cysts from Chemically Induced Liver Progenitors

Figure 3

Distributions of hepatocytes and cholangiocytes in 3D cysts (see also Figure S3). (a) Confocal microscopy images of 21 cysts stained with antibodies against Ck19 and Alb; single cyst was split into two spheroids; (i) and (ii) represent superior and inferior spheroids, respectively. (b) Percentages of Ck19⁺ (red), Alb⁺ (green), and Ck19⁺Alb⁺ (yellow) cells in 21 cysts.

(a)

(b)