Intra-Bone Marrow Administration of Mesenchymal Stem/Stromal Cells Is a Promising Approach for Treating Osteoporosis

<div>The characteristics of Sca-1-sorted MSCs. (a) Fluorescence immunostaining of Sca-1. (b) Cell number analysis after 1 week of culture. (c) ALP assay after 1 week of culture. (d) A schematic of the coculture assay to assess the ability of nonsorted or Sca-1-sorted MSCs to inhibit osteoclastogenesis. BMC: bone marrow cells; OC: osteoclasts. (e) After 1 week of coculture, the lower wells were subjected to TRAP staining. Arrows indicate osteoclasts. 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Stem Cells International

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Figure 2

Figure 2: Intra-Bone Marrow Administration of Mesenchymal Stem/Stromal Cells Is a Promising Approach for Treating Osteoporosis 