Intra-Bone Marrow Administration of Mesenchymal Stem/Stromal Cells Is a Promising Approach for Treating Osteoporosis

Figure 4

The effect of systemic administration of Sca-1-sorted MSCs via an intravenous or intra-bone marrow route (OVX+Sca-1-iv or OVX+Sca-1-ib mice, respectively) on bone parameters. (a) Representative micro-CT photographs of the right femurs of Sham, OVX, OVX+Sca-1-iv, and OVX+Sca-1-ib mice. (b) DEXA analysis of bone mineral content. (c) DEXA analysis of cross-sectional bone area (bone thickness). (d) DEXA analysis of BMD.

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