Systemic Infusion of Expanded CD133⁺ Cells and Expanded CD133⁺ Cell-Derived EVs for the Treatment of Ischemic Cardiomyopathy in a Rat Model of AMI

Figure 3

Echocardiographic evaluation of end-systolic and end-diastolic volume. Comparison of left ventricular end-systolic volume (a) and left ventricular end-diastolic volume (c) within each group pre- and posttreatment. Representative two-dimensional echocardiographic images of end-systolic volume (b) and end-diastolic volume (d) in a healthy animal of the control group. EVs: transplanted with expanded CD133⁺ cell-derived EVs; CD133⁺: transplanted with expanded CD133⁺ cells; vehicle: treated with PBS; control: healthy animals. Significant difference between pre- and posttreatment moments of each group (). Data are represented as median, minimum and maximum values, and SEM bars ( to 8 per group).

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