Atypical Mesenchymal Stromal Cell Responses to Topographic Modifications of Titanium Biomaterials Indicate Cytoskeletal- and Genetic Plasticity-Based Heterogeneity of Cells

<div>Morphological adaptation of MSCs on polished Ti. (a) Cells with a prominent nucleus and circumferentially spread cell membrane at 5 min post seeding. At (b) 15 min and (c) 30 min, cellular spreading had increased with some cells appearing comparatively rounded by this time. (d) By 1 h, most cells displayed a uniform circumferential spread over the surface. By (e) 3 h and (f) 24 h, cells had adapted an irregular and stretched polygonal morphology.</div>

Stem Cells International

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Figure 2: Atypical Mesenchymal Stromal Cell Responses to Topographic Modifications of Titanium Biomaterials Indicate Cytoskeletal- and Genetic Plasticity-Based Heterogeneity of Cells 

Figure 2 | Atypical Mesenchymal Stromal Cell Responses to Topographic Modifications of Titanium Biomaterials Indicate Cytoskeletal- and Genetic Plasticity-Based Heterogeneity of Cells 