Atypical Mesenchymal Stromal Cell Responses to Topographic Modifications of Titanium Biomaterials Indicate Cytoskeletal- and Genetic Plasticity-Based Heterogeneity of Cells

<div>Morphological adaptation of MSCs on the modSLA Ti surface. MSCs exhibited similar morphological adaptations as when seeded on the SLA. (a–c) MSCs appeared very rounded at 5, 15, and 30 min post seeding. (d) MSCs displayed extensions emanating across the surface by 60 min and had (e) begun exhibiting a stretched asymmetric form by 3 h that continually progressed till 24 h (f).</div>

Stem Cells International

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Figure 4: Atypical Mesenchymal Stromal Cell Responses to Topographic Modifications of Titanium Biomaterials Indicate Cytoskeletal- and Genetic Plasticity-Based Heterogeneity of Cells 

Figure 4 | Atypical Mesenchymal Stromal Cell Responses to Topographic Modifications of Titanium Biomaterials Indicate Cytoskeletal- and Genetic Plasticity-Based Heterogeneity of Cells 