Directional Topography Influences Adipose Mesenchymal Stromal Cell Plasticity: Prospects for Tissue Engineering and Fibrosis

<div>Surface topography characterization. (a) AFM images of the ten different ranges (small to large: R1-R11) of the two topographical directional gradients (nanometer scale and micrometer scale) along the PDMS substrate. Also shown is the flat PDMS control. Scale bars are 4 <i>μ</i>m and apply to all images. (b) Dependence of the wavelength and amplitude of created wrinkle gradients. The microgradient surface (blue) starts where the nanogradient surface (green) ends with respect to wavelength and amplitude. 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Stem Cells International

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Figure 2

Figure 2: Directional Topography Influences Adipose Mesenchymal Stromal Cell Plasticity: Prospects for Tissue Engineering and Fibrosis 