CD8+γδ T Cells Are More Frequent in CMV Seropositive Bone Marrow Grafts and Display Phenotype of an Adaptive Immune Response

<div>Vγ9- subsets within CMV+ grafts are enriched with an effector phenotype. (a) A representative FACS plot showing memory phenotype in Vγ9- subsets of CMV- and CMV+ grafts. (b) Proportions of naïve (CD27+CD45RO-), CM (CD27+CD45RO+), EM (CD27low/-CD45RO+), TE (CD27low/-CD45RO-) γδ T cells among Vγ9- subset of CMV- grafts and CMV+ grafts. Repeated measures ANOVA is used. Proportions of effector (CD27low/-CD45RO-/+) γδ T cells (c) and naïve γδ T cells (d) in Vγ9- and Vγ9+ subsets in CMV+ and CMV- grafts. ANOVA is used. Bar and whiskers represent the mean and S.E.M.</div>

Stem Cells International

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Figure 2

Figure 2: CD8+γδ T Cells Are More Frequent in CMV Seropositive Bone Marrow Grafts and Display Phenotype of an Adaptive Immune Response