Human Adipose-Derived Stem Cells Promote Seawater-Immersed Wound Healing by Activating Skin Stem Cells via the EGFR/MEK/ERK Pathway

<div>Ki67 and CK19 expression during wound repair after SW and hADSC treatments. The number and proportion of proliferating cells, as determined by Ki67 immunohistochemical and immunofluorescence (red) (a–d). The number and proportion of skin stem cells, as determined by cytokeratin 19 immunohistochemical and immunofluorescence (red) (e–h). DAPI staining shows the nuclei of tissues (blue). The number and proportion of proliferating cells or skin stem cells in the control group and the SW+hADSC group were significantly higher than those in the SW group. 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Stem Cells International

fig5

Figure 5

Figure 5: Human Adipose-Derived Stem Cells Promote Seawater-Immersed Wound Healing by Activating Skin Stem Cells via the EGFR/MEK/ERK Pathway 