Genes Involved in the Transcriptional Regulation of Pluripotency Are Expressed in Malignant Tumors of the Uterine Cervix and Can Induce Tumorigenic Capacity in a Nontumorigenic Cell Line

<div>Pluripotency factors are expressed in CC with different clinical outcomes. OSKM-N factors are overexpressed in cervical cancer tumor cells (arrows). P16<sup>INK4A</sup> was used as an indirect indicator of the presence of HPV and the degree of epithelial injury. The expression of OCT4, SOX2, and KLF4 was examined in 44 CC tissues from which the clinical response to treatment was known. Representative images of four samples are shown. ×40 magnification.</div>

Stem Cells International

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Figure 6

Figure 6: Genes Involved in the Transcriptional Regulation of Pluripotency Are Expressed in Malignant Tumors of the Uterine Cervix and Can Induce Tumorigenic Capacity in a Nontumorigenic Cell Line 

Figure 6 | Genes Involved in the Transcriptional Regulation of Pluripotency Are Expressed in Malignant Tumors of the Uterine Cervix and Can Induce Tumorigenic Capacity in a Nontumorigenic Cell Line 