Adipose-Derived Mesenchymal Stem Cells Promote M2 Macrophage Phenotype through Exosomes

Figure 1

AdMSCs induce macrophage M2 polarization. (a) qPCR analysis of coculture of AdMSCs with PBMCs for 24 h revealed increased gene expression of Arg1 (M2 macrophage marker). (b) Expression of CD206 in PBMCs after coculture as assessed by flow cytometry. (c) PBMCs were cocultured with AdMSCs for 24 h, then stained with CD206 (M2 macrophage marker) antibody by immunofluorescent staining (). The percentage of CD206-positive cells was determined by counting the number of stained cells. The data are expressed as the of three independent experiments. , .

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