Islet1 and Brn3 Expression Pattern Study in Human Retina and hiPSC-Derived Retinal Organoid

Figure 5

Brn3a expression in human fetal retina, retinal organoid, and rhesus retina. (a) Real-time PCR demonstrated the various expression of Brn3a, b, and c among retinal organoid, fetal retina, adult retina, rhesus retina, and Rb tissue. (b) Considering the rapidly decrease of RGC population in later developmental stage, Brn3a, b, and c expression levels were normalized with RBPMS expression. (c) Brn3a staining in human fetal retina. (d) Costaining of Brn3a and RBPMS in adult rhesus retina. (e–e) Immunostaining of Brn3a and Brn3 in Fwk 16 fetal retina. (f and f) Cell counting of central (f) and peripheral (f) Fwk 16 fetal retina.

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