Islet1 and Brn3 Expression Pattern Study in Human Retina and hiPSC-Derived Retinal Organoid

<div>Islet1 expression and postmitotic amacrine marker, AP2<i>α</i>. (a–f) Amacrine cell developed as early as Fwk 9 and then organized in the inner side of the INL, without coexpression of Islet1. (g–l) In the retinal organoid, AP2<i>α</i>-positive amacrine cell was observed at Dwk 13, later than in the fetal retina. Until Dwk 16, the number of amacrine cells obviously increased but was organized as rosettes. 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Stem Cells International

fig6

Figure 6

Figure 6: Islet1 and Brn3 Expression Pattern Study in Human Retina and hiPSC-Derived Retinal Organoid 