Metformin Inhibits the Expression of Biomarkers of Fibrosis of EPCs In Vitro

Figure 8

Live-dead cell staining: (a) control; (b): 20 ng TGF-β1; (c) TGF-β1+0.5 mM metformin; (d) TGF-β1+1 mM metformin; (e) TGF-β1+2 mM metformin. No obvious apoptosis of EPCs was observed in any group. However, there were some cellular morphological changes in (b) to (e); some stellate and flat cells were observed in these groups.

(a)

(b)

(c)

(d)

(e)