Adipose-Derived Mesenchymal Stem Cells Enhance Ovarian Cancer Growth and Metastasis by Increasing Thymosin Beta 4X-Linked Expression

<div>ADSCs promote the proliferation, migration, and invasion of ovarian cancer cells in vitro. (a) Representative results of CCK-8 assays in SKOV3, HO8910, and ES2 cells are shown. Cancer cells were treated with ADSC CM. (b) Representative results of scratch-wound assays for the detection of ovarian cancer cell mobility (scale bar, 100 <i>μ</i>m). (c) Representative results of Transwell assays in ovarian cancer cells are shown. The number of cancer cells that migrated through the 8 <i>μ</i>m Transwell membrane pores was counted to determine changes in the invasive capabilities in response to ADSC CM (scale bar, 50 <i>μ</i>m).</div>

Stem Cells International

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Figure 1: Adipose-Derived Mesenchymal Stem Cells Enhance Ovarian Cancer Growth and Metastasis by Increasing Thymosin Beta 4X-Linked Expression 