Adipose-Derived Mesenchymal Stem Cells Enhance Ovarian Cancer Growth and Metastasis by Increasing Thymosin Beta 4X-Linked Expression

<div>ADSCs enhance the proliferation, migration, and invasion of ovarian cancer cells by increasing TMSB4X expression in nude mouse models. (a) An in vivo imaging system was used to monitor SKOV3 xenograft luminescence activity, which represented tumour growth and metastasis. (b) Living Image software was used to analyse tumour bioluminescence intensity weekly. Quantitative results regarding the normalized image counts are shown. (c) Immunohistochemical analysis results regarding Ki67 and TMSB4X expression in the orthotopic tumour xenografts are shown. 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Stem Cells International

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Figure 4

Figure 4: Adipose-Derived Mesenchymal Stem Cells Enhance Ovarian Cancer Growth and Metastasis by Increasing Thymosin Beta 4X-Linked Expression 