Expression of Potential Dermal Progenitor Cell Markers in the Tumour and Stroma of Skin Adnexal Malignant and Benign Tumours

Figure 4

Nestin expression profile: scalp skin with positive staining of the outer root sheath cells of the hair follicle (a) in the dermal interface of sebaceous glands (b) and the tumour-stroma interaction (TSI) site within the core of the tumour and the invasive margin (IM) of the tumour of a nodular basal cell carcinoma (c, d), adenoid (e), and nodular (f) basal cell carcinoma with Nestin-positive cells at the invasive margin (IM) of the tumour (black arrows). Expression in early porocarcinoma at the invasive margin (g and h) but also within the inflammatory infiltrate ((h), as indicated by black arrows and the two small pictures below in higher magnification). Low-grade sebaceous carcinoma (i) with positive basal cells within the tumour stroma interface (TSI).