Research Article
Expression of Potential Dermal Progenitor Cell Markers in the Tumour and Stroma of Skin Adnexal Malignant and Benign Tumours
Table 1
Expression profile of potential dermal progenitor markers in normal skin (epidermis and dermis).
| Antibody | CRABP1 | Nestin | Ephrin B2C | Ephrin B2N |
| Anatomical structure | | | | |
| Epidermis | Str. corneum | 0 | 0 | 0 | 0 | Str. granulosum | 0 | 0 | 0 | 0 | Str. spinosum | 0 | 0 | 0 | 0 | Str. basale | 0 | 0 | 0 | 0 |
| Hair follicle | Epidermal HRS | 0 | 0 | 0 | 0 | Outer HRS | 0 | 2 | 1 | 1 | Inner HRS | 0 | 0 | 1 | 1 |
| Cortex | Hair matrix | 0 | 0 | 1 | 1 | Presumptive cortex | 0 | 0 | 3 | 1 |
| Sebaceous gland | Luminal | 0 | 0 | 2 | 0 |
| Acinus | Basal | 0 | 0 | 0 | 0 |
| Sebaceous gland | Basal sebocytes | 1 | 0 | 0 | 0 | Suprabasal sebocytes | 2 | 0 | 2 | 1 |
| Eccrine sweat glands | | 0 | 0 | 0 | 0 |
| Acrosyringium | Basal cells | 0 | 0 | 0 | 0 | Luminal cells | 0 | 0 | 0 | 0 |
| Dermis | Epidermal/dermal interface | 2 | 1 | 0 | 0 | Papillary dermis | 1 | 1 | 1 | 0 | Reticulary dermis | 0 | 1 | 0 | 0 |
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0 = no expression detectable. 1 = <33% of cells stained positively. 2 = 33-66% of cells stained positively. 3 = >66% of cells stained positively.
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