Review Article
Immunomodulatory Functions of Mesenchymal Stem Cells in Tissue Engineering
Figure 2
In addition to direct immunosuppressive inhibition, T cells can induce Treg cells under the regulation of MSCs and vice versa. Blue arrow: cytokine secretion, dotted arrow: inhibition of MSCs and Treg, black arrow: positive promotion, and green arrow: differentiation of T cells to Treg.