The Late Osteoblast/Preosteocyte Cell Line MLO-A5 Displays Mesenchymal Lineage Plasticity <i>In Vitro</i> and <i>In Vivo</i>

<div>(a) <i>In vitro</i> fat droplet formation by MLO-A5 cultured under adipogenic conditions for the times indicated, visualised by Oil Red O staining. (b) Real-time RT-PCR analysis of <i>Cebpa</i>, <i>Pparg</i>, <i>Adipoq</i>, <i>Slc2a4</i>, and <i>Fabp4</i> gene expression in MLO-A5 cultures under adipogenic conditions. Data are shown as mean <svg height="12.6199pt" id="M19" style="vertical-align:-3.38375pt" version="1.1" viewbox="-0.0498162 -9.23615 110.344 12.6199" width="110.344pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M54 437L27 408L31 397H101V103C101 37 94 32 30 26V0H266V25C187 33 180 36 180 110V397H288C299 404 304 428 298 437H180V477C179 562 190 610 203 630C214 647 230 659 256 659C289 659 318 641 337 622C346 612 355 612 364 619C374 627 380 635 383 643C388 655 387 667 378 678C362 697 333 710 299 712C260 707 225 689 189 659C135 613 119 563 112 541S101 490 101 458V437H54Z"></path></g><g transform="matrix(.013,0,0,-0.013,4.905,0)"><path d="M257 449C165 449 37 374 37 209C37 98 119 -12 256 -12C355 -12 473 65 473 226C473 349 381 449 257 449ZM244 416C333 416 380 320 380 204C380 67 329 21 267 21C184 21 130 115 130 241C130 354 184 416 244 416Z"></path></g><g transform="matrix(.013,0,0,-0.013,11.444,0)"><path 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Stem Cells International

fig3

Figure 3

Figure 3: The Late Osteoblast/Preosteocyte Cell Line MLO-A5 Displays Mesenchymal Lineage Plasticity <i>In Vitro</i> and <i>In Vivo</i> 

Stem Cells International

The Late Osteoblast/Preosteocyte Cell Line MLO-A5 Displays Mesenchymal Lineage Plasticity In Vitro and In Vivo

Figure 3