Safety and Localization of Mesenchymal Stromal Cells Derived from Human Adipose Tissue-Associated Hyaluronic Acid: A Preclinical Study

Figure 3

Modification of expression of specific surface antigen along passages in adipose mesenchymal stromal cells. (a) First passage. (b) Second passage. (c) Third passage. It is possible to visualize the presence of hematopoietic cells (CD45⁺) and precursor cells (CD34⁺) at the beginning of the culture. Throughout the passages, the population of mesenchymal cells became more homogeneous; besides that, they express similar levels of CD73 and CD105 specific surface antigens, with reduction of the coefficient of variation (width) of histograms.