Safety and Localization of Mesenchymal Stromal Cells Derived from Human Adipose Tissue-Associated Hyaluronic Acid: A Preclinical Study

Table 3

Evaluation of the change in the water consumption of the test systems assessed for up until six weeks after the subcutaneous infusion of the test substances.

Weeks	Water consumption (mL)
	Groups	Saline (NaCl)		ACS		HA 1%		ASC+HA 1%		FAC
	Animals ()	Media	SD	Media	SD	Media	SD	Media	SD	Media	SD
1-2	5	250,80	25,74	255,60	2036	286,20	3,11	236,60	34,22	234,40	22,63
1-4	5	218,25	68,31	241,25	14,30	253,40	15,83	259,00	35,49	248,50	39,94
1-6	5	281,17	59,34	269,37	30,93	242,40	34,04	226,93	39,67	319,00	65,70

: no. of animals; NaCl: sodium chloride; HA: hyaluronic acid; ASC: adipose derived stromal cells; FAC: Freund’s adjuvant complete. ASC+HA 1%. ANOVA with Bonferroni’s correction (Bonferroni post hoc test). FAC vs. ASC+HA 1%.