Mesenchymal Stem Cell-Based Therapy for Allergic Rhinitis

Figure 1

Schematic illustration of soluble factors for MSCs-mediated immunosuppression. MSCs exert their immunosuppression effects by secreting various soluble factors. MSCs inhibit the proliferation and activation of T cells, suppress B cell differentiation, inhibit the maturation and differentiation of DCs, suppress the proliferation, cytotoxicity, and cytokine production of NK cells. MSCs also induce Tregs expansion.