Antioxidant Properties of Tonsil-Derived Mesenchymal Stem Cells on Human Vocal Fold Fibroblast Exposed to Oxidative Stress

<div>Viability and proliferation of human vocal fold fibroblasts (hVFFs) after <i>tert</i>-butyl hydroperoxide (tBHP) treatment and coculture with tonsil-derived mesenchymal stem cells (TMSCs). (a) Cell viability was significantly decreased following treatment with tBHP in a dose-dependent manner. (b) Of the different hVFF : TMSC ratios examined, 1 : 0.5 ratio exhibited significant recovery of cell viability. (c) Representative flow cytometry results and integrated proportion for EdU<sup>+</sup> proliferating cells. Results are 3 technical replicates of TMSC from one donor. Representative results from two different TMSCs with similar tendency were presented. For multigroup comparison, ANOVA followed by the Bonferroni post hoc test was used for statistics. 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Stem Cells International

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Figure 1

Figure 1: Antioxidant Properties of Tonsil-Derived Mesenchymal Stem Cells on Human Vocal Fold Fibroblast Exposed to Oxidative Stress 