Mesenchymal Stem Cell Therapy Using Human Umbilical Cord in a Rat Model of Autoimmune-Induced Premature Ovarian Failure

Figure 2

Effects of modeling and UCMSC transplantation on the estrus cycle of rats. (a) Four patterns of abnormal estrus cycles were graded with the severity of abnormality (I–IV) as follows: I: normal; II: regular cycles with a shortened estrus; III: irregular cycles with a prolonged diestrus and normal or prolonged estrus; IV: no cyclicity. The -axis represents the cycle day in proestrus, estrus, metestrus, and diestrus. (b) The total numbers of rats from the control and model groups that were categorized into the various estrus patterns (I–IV), . (c) The total numbers of rats from each group after UCMSC transplantation were categorized into the various estrus patterns (I–IV), .

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