TRAF6 Promotes Gastric Cancer Cell Self-Renewal, Proliferation, and Migration

<div>TRAF6 promoted stemness and inhibited differentiation in gastric cancer cells. (a) Western blot assay for the expressions of SOX2, N-cadherin, and E-cadherin in vector and TRAF6 plasmid-transfected HGC-27 cells. (b) Western blot assay for the expression of SOX2, N-cadherin, and E-cadherin in transfected NC and TRAF6 siRNA-transfected HGC-27 cells. (c) Mammospheres generated from single-cell cultures of NC and TRAF6 siRNA-transfected HGC-27 cells, imaged after 6 days of suspension culture (SF medium). 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Stem Cells International

fig5

Figure 5

Figure 5: TRAF6 Promotes Gastric Cancer Cell Self-Renewal, Proliferation, and Migration 