Functional Comparison between Healthy and Multiple Myeloma Adipose Stromal Cells

Figure 2

Phenotype and differentiation potential of HD and MM ASCs compared with autologous MSCs. (a) Expression of CD73, CD90, CD105, CD31, CD45, and CD200 in cells after primoculture. Data are mean % positive ( independent experiments). Adipogenic differentiation with triglyceride dosage (b), chondrogenic differentiation with glycosaminoglycan dosage (c), osteoblastic differentiation with quantification of alizarin red (d), and alkaline phosphatase activity (e) evaluated from all cell sources. Data are the ( independent experiments). (f) DKK1 secretion from HD/MM ASCs or MSCs. Data are the ( independent experiments). , , .

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