High Glucose Exacerbates TNF-<i>α</i>-Induced Proliferative Inhibition in Human Periodontal Ligament Stem Cells through Upregulation and Activation of TNF Receptor 1

<div>Protein expression of TNFR1 and TNFR2 in PDLSCs under high-glucose conditions. PDLSCs were cultured under normal glucose (G5.6) or high-glucose (G30) conditions. Protein expression of TNFR1 and TNFR2 was detected by western blotting. (a–c) Protein expression of TNFR1 was elevated by high-glucose treatment on day 2 and day 6. 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(d–f) Protein expression of TNFR2 was unchanged under high-glucose conditions on day 2 and day 6.</div>

Stem Cells International

fig2

Figure 2

Figure 2: High Glucose Exacerbates TNF-<i>α</i>-Induced Proliferative Inhibition in Human Periodontal Ligament Stem Cells through Upregulation and Activation of TNF Receptor 1 

Figure 2 | High Glucose Exacerbates TNF-α-Induced Proliferative Inhibition in Human Periodontal Ligament Stem Cells through Upregulation and Activation of TNF Receptor 1 