Transplantation of Stem Cells from Human Exfoliated Deciduous Teeth Decreases Cognitive Impairment from Chronic Cerebral Ischemia by Reducing Neuronal Apoptosis in Rats

<div>SHED express mesenchymal stem cell surface markers and can differentiate into osteogenic and neuron-like cells. (a, b) Expression of mesenchymal stem cell- (MSC-) specific surface markers in SHED. Positive expression was observed for CD73, CD90, and CD105, and negative expression was observed for CD34 and CD45. (c) Primary culture of SHED with CFU staining. (d) Alizarin red staining showed the mineralized nodule formation of SHED. (e, f) SHED differentiated into neuron-like cells, and expressed the neural cell marker <i>β</i>III-tubulin and the neural stem cell-specific marker Nestin. Scale bar: 70 <i>μ</i>m.</div>

Stem Cells International

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Figure 2: Transplantation of Stem Cells from Human Exfoliated Deciduous Teeth Decreases Cognitive Impairment from Chronic Cerebral Ischemia by Reducing Neuronal Apoptosis in Rats 

Figure 2 | Transplantation of Stem Cells from Human Exfoliated Deciduous Teeth Decreases Cognitive Impairment from Chronic Cerebral Ischemia by Reducing Neuronal Apoptosis in Rats 