Screening Genes Promoting Exit from Naive Pluripotency Based on Genome-Scale CRISPR-Cas9 Knockout

<div>RT-qPCR analysis of the expression of three pluripotency factors in wild-type OG2 mESCs transfected with plko-shRNA of (a) <i>Tcf7l1</i>, (b) <i>p53</i>, (c) <i>Jarid2</i>, and (d) <i>Fbxw7</i> and treated by withdrawing 2i/LIF. 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Stem Cells International

fig5

Figure 5

Figure 5: Screening Genes Promoting Exit from Naive Pluripotency Based on Genome-Scale CRISPR-Cas9 Knockout 