Stem Cells International

Review Article

The Clinical Trials of Mesenchymal Stromal Cells Therapy

Table 2

Active clinical trials on mesenchymal stromal/stem cell-based therapy started during 2016-2020 (U. S. National Library of Medicine).
Organ systemDisease/syndromePhaseDateCountrySourceTransplantationCT code
CardiovascularHypoplastic left heart syndrome1 and 22018United StatesBone marrowAllotransplantNCT03525418
GastrointestinalCystic fibrosis12016United StatesBone marrowAllotransplantNCT02866721
GastrointestinalDiabetes1 and 22017United StatesNDAllotransplantNCT02886884
GastrointestinalInflammatory bowel1 and 22017JordanWharton’s jellyAllotransplantNCT03299413
GastrointestinalPrimary sclerosing cholangitis1 and 22017ChinaUmbilical cordAllotransplantNCT03516006
GastrointestinalXerostomia12019DenmarkAdipose tissueAllotransplantNCT03874572
ImmuneGraft versus host disease1 and 22016SpainAdipose tissueAutotransplantNCT02687646
ImmuneGraft versus host disease12018United StatesUmbilical cord
Wharton’s jelly		AllotransplantNCT03158896
IntegumentaryEpidermolysis bullosa1 and 22018SpainBone marrowAllotransplantNCT04153630
IntegumentaryEpidermolysis bullosa1 and 22019United KingdomSkinAllotransplantNCT03529877
IntegumentaryInflammation1 and 22018United StatesBone marrowAllotransplantNCT03059355
IntegumentaryPsoriasis1 and 22017ChinaAdipose tissueAllotransplantNCT03265613
NervousAlcoholism1 and 22018United StatesNDAllotransplantNCT03265808
NervousAlzheimer’s disease1 and 22020United StatesAdipose tissueAutotransplantNCT04228666
NervousAlzheimer’s disease12016United StatesBone marrowAllotransplantNCT02600130
NervousAmyotrophic lateral sclerosis32017United StatesUmbilical cordAllotransplantNCT03280056
NervousCerebral palsy1 and 22016JordanBone marrowAutotransplantNCT03078621
NervousCerebral palsy22017IranUmbilical cordAllotransplantNCT03795974
NervousCerebral palsy1 and 22018United StatesUmbilical cordAllotransplantNCT03473301
NervousHuntington disease22018BrazilDental pulpAllotransplantNCT03252535
NervousHuntington disease12017BrazilDental pulpAllotransplantNCT02728115
NervousMultiple sclerosis22018United StatesBone marrowAutotransplantNCT03355365
NervousMultiple sclerosis22019United StatesNDAutotransplantNCT03799718
NervousMultiple system atrophy12018KoreaBone marrowAutotransplantNCT04495582
NervousNervous injury1 and 22017ChinaUmbilical cordAllotransplantNCT03291366
NervousParkinson’s disease22017BelarusBone marrowAutotransplantNCT04146519
NervousSpinal cord injury12017United StatesAdipose tissueAutotransplantNCT03308565
RespiratoryCOVID-191 and 22020SpainAdipose tissueAllotransplantNCT04366323
RespiratoryCOVID-1922020United StatesAdipose tissueAllotransplantNCT04362189
RespiratoryCOVID-1922020United StatesAdipose tissueAutotransplantNCT04349631
RespiratoryCOVID-191 and 22020FranceUmbilical cord
Wharton’s jelly		AllotransplantNCT04333368
SkeletalKnee osteoarthritis12019United StatesAdipose tissueAutotransplantNCT04043819
SkeletalLateral epicondylitis22018KoreaAdipose tissueAllotransplantNCT03449082
SkeletalOsteoarthritis22017KoreaAdipose tissueAutotransplantNCT03509025
SkeletalOsteoarthritis32019KoreaAdipose tissueAutotransplantNCT03990805
SkeletalOsteoarthritis12016JordanBone marrowAutotransplantNCT03067870
UrinaryFistula12017United StatesAdipose tissueAutotransplantNCT02808208
UrinaryKidney injury1 and 22017United StatesBone marrowAllotransplantNCT03015623
UrinaryNephrosis22016ChinaBone marrowAutotransplantNCT02966717
ND: no data.