Cloning and Embryo Splitting in Mammalians: Brief History, Methods, and Achievements

Table 1

Comparing blastomere biopsy and bisection.

	Growth stage of embryo	Advantages	Disadvantages	References
Blastomere biopsy	Cleavage stage	Applicable for preimplantation	Low efficiency in 8-cell stage in some species	[34]
Bisection	Morula and blastocyst	Creating MZ twinning in mice, cow, goat, & pig	Cell damage	[35]