Cloning and Embryo Splitting in Mammalians: Brief History, Methods, and Achievements

Table 4

Human embryo splitting.

Embryo sample	Method	Results	Reference
4-cell	Biopsy	In vitro developing into blastocysts	[59]
4-cell	Biopsy	Harvesting human ESCs (hESCs)	[60]
2- to 5- & 6- to 8-cell	Biopsy	First twined human embryos	[28]
Morula	Bisection	Harvesting hESCs	[61]
4-cell	Biopsy	Harvesting hESCs	[62]
Blastocyst	Bisection	Harvesting hESCs	[63]
4-cell	Biopsy	First pregnancy by embryo splitting	[64]
4-cell	Biopsy	Harvesting first Swiss hESC (CH-ES1)	[65]
4-cell	Biopsy	Harvesting hESCs	[66]