|
Factor overexpressed | MSC source | Method | Disease | Reference |
|
Akt | Human umbilical cord | Adenovirus | Acute myocardial infarction | [187] |
Angiotensin II type 2 receptor | Human bone marrow | Lentivirus | LPS-induced acute lung injury | [188] |
Arginine decarboxylase | Human adipose tissue | Retrovirus | Spinal cord injury | [189] |
Basic fibroblast growth factor (bFGF) | Human bone marrow | Lentivirus | Angiogenesis | [190] |
Brain-derived neurotrophic factor (BDNF) | Human umbilical cord blood | Plasmid transfection | Neurological injury and disease | [191] |
Human bone marrow | Lentivirus | Neuronal degeneration | [192] |
C-C chemokine receptor type 2 (CCR2) | Human bone marrow | Lentivirus | Ischemic stroke | [193] |
CXC chemokine receptor 4 (CXCR4) | Human umbilical cord | Lentivirus | Radiation- induced lung injury | [194] |
Cytosine deaminase (CD) and herpes simplex virus thymidine kinase (HSV-tk) | Human umbilical cord blood | Lentivirus | Ovarian cancer | [195] |
Ephrin-B2 | Human bone marrow | Plasmid transfection | Ischemic tissues | [196] |
Forkhead box protein (Foxa2) | Human adipose tissue | Plasmid transfection | Acute liver injury | [197] |
Glial-derived neurotrophic factor (GDNF) | Human adipose | Lentivirus | Renal interstitial fibrosis | [198] |
Human bone marrow | Adenovirus | Nephrotoxic serum nephritis | [199] |
Glucocorticoid-induced tumour necrosis factor-related receptor (GITR) | Human bone marrow | Plasmid transfection | Small cell lung cancer | [200] |
Granulocyte chemotactic protein-2 (GCP-2) | Human adipose tissue | Lentivirus | Myocardial infarction | [201] |
Heme oxygenase-1 (HO-1) | Human embryonic stem cell | Lentivirus | Myocardial infarction | [202] |
Hepatocyte growth factor (HGF) | Human bone marrow | Retrovirus | Bladder outlet obstruction | [203] |
Human umbilical cord | Lentivirus | Myocardial infarction | [204] |
Human bone marrow | Adenovirus | Liver fibrosis | [205] |
Human umbilical cord | Adenovirus | Injured sinonasal mucosa | [206] |
Human umbilical cord | Adenovirus | Parkinson’s disease | [207] |
Human umbilical cord blood | Plasmid transfection | Liver fibrosis | [208] |
Human bone marrow | Lentivirus | Spinal cord injury | [209] |
Hepatocyte nuclear factor 4a (HNF 4a) | Human umbilical cord | Lentivirus | Hepatocellular carcinogenesis | [210] |
Human N-cadherin | Human umbilical cord blood | Lentivirus | Myocardial infarction | [211] |
Hypoxia inducible factor-1a (HIF-1a) | Human bone marrow | Lentivirus | Angiogenesis | [212] |
IL-4 | Human adipose tissue | Lentivirus | Multiple sclerosis | [213] |
IL-10 | Human amniotic fluid | Human amniotic fluid | Liver fibrosis | [214] |
Human bone marrow | AAV | Acute ischemic stroke | [215] |
Leptin | Human bone marrow | Lentivirus | Myocardial infarction | [216] |
LIM-homeobox transcription factor islet-1 (ISL1) | Human bone marrow | Lentivirus | Myocardial infarction | [217] |
miR-101-3p | Human bone marrow | Lentivirus | Oral cancer | [217] |
miR-16-5p | Human bone marrow | Plasmid transfection | Colorectal cancer | [218] |
miR-199a | Human bone marrow | Plasmid transfection | Glioma | [218] |
miR-199a-3p | Human bone marrow | miRNA transfection | Renal ischemia/reperfusion injury | [219] |
miR-let-7d or miR-154 | Human bone marrow | Lentivirus | Lung injury | [220] |
miRNA-181 | Human umbilical cord blood | Lentivirus | Myocardial ischemia-reperfusion injury | [221] |
Neuregulin 1 (NRG1) | Human adipose tissue | Adenovirus | Cerebral ischemia | [222] |
Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) | Human amniotic fluid | Lentivirus | Acute lung injury | [194] |
Oct4 and Sox2 | Human adipose tissue | Plasmid transfection | Liver injury | [223] |
PARKIN | Human Wharton’s jelly | Plasmid transfection | Parkinson’s disease | [224] |
Pigment epithelial-derived factor (PEDF) | Human bone marrow | Lentivirus | Hepatocellular carcinoma | [225] |
SRC3-specific short hairpin RNA (sh-SRC3) | Human bone marrow | Lentivirus | Multiple myeloma | [226] |
sST2 | Human adipose tissue | Lentivirus | Occupational asthma | [227] |
Human adipose tissue | Lentivirus | Endotoxin-induced acute lung injury | [228] |
Thioredoxin-1 (Trx-1) | Human umbilical cord | Adenovirus | Acute radiation injury | [229] |
Tissue matrix metalloproteinase inhibitor 2 (TIMP2) | Human umbilical cord | Lentivirus | Myocardial infarction | [230] |
TNF-related apoptosis-inducing ligand (TRAIL) | Human bone marrow | Lentivirus | Non-small-cell lung cancer | [231] |
Human adipose tissue | Plasmid transfection | Non-small-cell lung cancer | [232] |
Human adipose tissue | Lentivirus | Glioblastoma multiforme | [233] |
Transforming growth factor b1 (TGF-b1) | Human bone marrow | Lentivirus | Angiogenesis | [190] |
Vascular endothelial growth factor (VEGF) | Human bone marrow | Lentivirus | Peripheral nerve injury | [234] |
|