SDF-1α Facilitates Mesenchymal Stem Cells to Induce Regulatory B Cell Differentiation from Patients with Immune Thrombocytopenia

Figure 5

SDF-1α regulates the effects of MSCs on B cells through changing the miR-133 level. (a) Transfected by miR-133 inhibitor, the ability of MSCs to facilitate CD19⁺CD24^hiCD38^hi CD19⁺ B cells was depressed. (b) Transfected by miR-133 inhibitor, the ability of MSCs to facilitate IL-10-producing CD19⁺ B cells was depressed. .

(a)

(b)