Curcumin and Mesenchymal Stem Cells Ameliorate Ankle, Testis, and Ovary Deleterious Histological Changes in Arthritic Rats <i>via</i> Suppression of Oxidative Stress and Inflammation

<div>Schematic figure showing the mode of actions of CFA to induce arthritis <i>via</i> increasing LPO and TNF-<i>α</i> (Th1 cytokine) and decreasing IL-10 (Th2), thereby resulting in synovial hyperplasia and joint, testis, and ovary necrosis, and inflammation. The treatment with curcumin and/or MSCs can counteract these actions <i>via</i> enhancing the antioxidant defense system and anti-inflammatory mechanisms. →: activation; ┴: inhibition.</div>

Stem Cells International

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Figure 10

Figure 10: Curcumin and Mesenchymal Stem Cells Ameliorate Ankle, Testis, and Ovary Deleterious Histological Changes in Arthritic Rats <i>via</i> Suppression of Oxidative Stress and Inflammation 

Figure 10 | Curcumin and Mesenchymal Stem Cells Ameliorate Ankle, Testis, and Ovary Deleterious Histological Changes in Arthritic Rats via Suppression of Oxidative Stress and Inflammation 