Curcumin and Mesenchymal Stem Cells Ameliorate Ankle, Testis, and Ovary Deleterious Histological Changes in Arthritic Rats via Suppression of Oxidative Stress and Inflammation

Figure 3

Photomicrographs of sections in the ankles of male rats. (a) From the RA group showing necrosis of articular cartilage (↗). The insert shows pannus formation (↙). (b) From the RA group showing necrosis of articular cartilage (↓) and inflammatory cell infiltration (IF). (c–e) From arthritic-treated groups with curcumin, MSCs, and a combination of curcumin and MSCs, respectively, showing a nearly normal structure of articulating cartilage (AC), synovial cavity (SyC), sponge bone (SB), and bone marrow (BM).

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