Curcumin and Mesenchymal Stem Cells Ameliorate Ankle, Testis, and Ovary Deleterious Histological Changes in Arthritic Rats via Suppression of Oxidative Stress and Inflammation

Table 12

Protective effect of MSCs and curcumin against CFA-induced changes in LPO; GSH concentration; and GST, GPx, and SOD activities in serum of all experimental groups.

Parameter		Group
		Normal	CMC/PBS	Curcumin	MSCs	Arthritic group	Arthritic group treated with curcumin	Arthritic group treated with MSCs	Arthritic group treated with MSCs and curcumin
LPO (nmol/mL)	Male rats	^a	^a	^a	^a	^b	^a	^a	^a
	Female rats	^a	^a	^a	^a	^c	^d	^a	^a
GSH (nmol/mL)	Male rats	^a	^a	^a	^a	^b	^a	^a	^a
	Female rats	^a	^a	^a	^a	^b	^a	^a	^a
GST (U/mL)	Male rats	^a	^a	^a	^a	^b	^d	^d	^a
	Female rats	^a	^a	^a	^a	^c	^d	^d	^a
GPx (U/mL)	Male rats	^a	^a	^a	^a	^b	^d	^d	^a
	Female rats	^a	^a	^a	^a	^c	^d	^d	^a
SOD (U/mL)	Male rats	^a	^a	^a	^a	^b	^a	^a	^a
	Female rats	^a	^a	^a	^a	^c	^a	^a	^a

Data are expressed as . The number of animals in each group is six. In the same column, values with the same superscript letter are similar (nonsignificant, ), whereas others are significant (significant, ).