Key Markers and Epigenetic Modifications of Dental-Derived Mesenchymal Stromal Cells

Table 1

Characteristics of dental-derived MSCs.

Cell type	Origin	Multipotentiality (in vitro)	Application	References
DPSCs	Dental pulp tissue	Osteo/odontogenic	Immunoregulation	[213–217]
		Adipogenic	Angiogenesis
		Chondrogenic	Nerve injure treatment
		Vascular
		Neurogenic	Dentin/pulp complex formation
SHEDs	Human exfoliated deciduous teeth	Osteo/odontogenic	Angiogenesis	[46, 218–220]
		Adipogenic	Dental/pulp complex formation
		Chondrogenic
		Neurogenic
SCAPs	Apical papilla	Osteo/odontogenic	Dentin/pulp complex formation, spinal injure treatment; Angiogenesis	[221, 222]
		Adipogenic
		Neurogenic
PDLSCs	Periodontal ligament	Osteo/cementogenic	Immunosuppressive effects	[8, 223–225]
		Adipogenic	Periodontal disease
		Chondrogenic
		Neurogenic
DFCs	Dental follicle	Osteo/cementogenic	Periodontal tissue	[54, 226, 227]
		Odontogenic	Angiogenesis
		Adipogenic	Pulp tissue formation
		Chondrogenic
		Neurogenic
TGSCs	Apical papilla in the developing tooth germ	Adipogenic	Liver disease; Dental defects	[32, 228, 229]
		Osteogenic
		Neurogenic
		Adipogenic
		Chondrogenic
		Endothelial
GMSCs	Gingiva	Osteogenic	Nerve regeneration, mandibular defects	[31, 43, 230]
		Chondrogenic
		Neurogenic
		Adipogenic	Immunomodulatory properties