Characterization and Study of Gene Expression Profiles of Human Periodontal Mesenchymal Stem Cells in Spheroid Cultures by Transcriptome Analysis

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr class="thead"><td class="align_left">Gene</td><td class="align_center">Spheroid_FPKM</td><td class="align_center">Monolayer_FPKM</td><td class="align_center">Spheroid_vs_monolayer</td><td class="align_center"><svg height="9.39034pt" id="M88" style="vertical-align:-3.42943pt" version="1.1" viewbox="-0.0498162 -5.96091 6.50656 9.39034" width="6.50656pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M474 429L457 433C435 440 389 448 367 448C348 448 323 446 309 443C266 434 195 406 148 366C78 307 23 210 23 101C23 35 55 -12 92 -12C118 -12 146 1 196 35C247 70 311 130 346 173H348L281 -148C268 -211 256 -221 208 -229L191 -232L187 -257L433 -245L437 -219L411 -216C357 -210 350 -205 362 -140L427 207C447 315 461 381 474 429ZM387 387C379 337 363 262 355 236C318 180 201 57 142 57C126 57 112 81 112 128C112 205 150 321 220 376C244 395 280 403 312 403C345 403 370 396 387 387Z"></path></g></svg>_value</td></tr><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr><td class="align_left">AREG</td><td class="align_center">200.378</td><td class="align_center">0.263988</td><td class="align_center">9.56804</td><td class="align_center">0.000412899</td></tr><tr><td class="align_left">STC1</td><td class="align_center">403.17</td><td class="align_center">1.17002</td><td class="align_center">8.42871</td><td class="align_center">0.000412899</td></tr><tr><td class="align_left">SLC16A6</td><td class="align_center">79.6871</td><td class="align_center">0.231565</td><td class="align_center">8.42678</td><td class="align_center">0.00660208</td></tr><tr><td class="align_left">CXCL8</td><td class="align_center">616.76</td><td class="align_center">2.14352</td><td class="align_center">8.16859</td><td class="align_center">0.00041289</td></tr><tr><td class="align_left">PTGS2</td><td class="align_center">801.382</td><td class="align_center">2.85902</td><td class="align_center">8.13083</td><td class="align_center">0.00041289</td></tr><tr><td class="align_left">PTHLH</td><td class="align_center">196.705</td><td class="align_center">0.99057</td><td class="align_center">7.63356</td><td class="align_center">0.00041289</td></tr><tr><td class="align_left">FAM20A</td><td class="align_center">53.1832</td><td class="align_center">0.286936</td><td class="align_center">7.5341</td><td class="align_center">0.00142828</td></tr><tr><td class="align_left">NR4A2</td><td class="align_center">79.2241</td><td class="align_center">0.506743</td><td class="align_center">7.28854</td><td class="align_center">0.00041289</td></tr><tr><td class="align_left">APOE</td><td class="align_center">118.754</td><td class="align_center">1.03351</td><td class="align_center">6.84429</td><td class="align_center">0.00041289</td></tr><tr><td class="align_left">IL11</td><td class="align_center">474.824</td><td class="align_center">6.36988</td><td class="align_center">6.21998</td><td class="align_center">0.00041289</td></tr><tr class="table-tr"><td colspan="5"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Among the DEGs between the spheroid and monolayer culture groups, we extracted genes with <span class="nowrap"><svg height="13.1953pt" id="M85" style="vertical-align:-3.8874pt" version="1.1" viewbox="-0.0498162 -9.3079 114.399 13.1953" width="114.399pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M495 163C480 117 462 85 444 65C421 39 387 34 332 34C290 34 256 36 236 47C218 57 213 77 213 131V526C213 612 222 616 301 622V650H40V622C122 616 128 611 128 526V126C128 41 120 34 36 28V0H489C498 31 519 126 525 157L495 163Z"></path></g><g transform="matrix(.013,0,0,-0.013,7.111,0)"><path d="M257 449C165 449 37 374 37 209C37 98 119 -12 256 -12C355 -12 473 65 473 226C473 349 381 449 257 449ZM244 416C333 416 380 320 380 204C380 67 329 21 267 21C184 21 130 115 130 241C130 354 184 416 244 416Z"></path></g><g transform="matrix(.013,0,0,-0.013,13.792,0)"><path d="M463 437C426 431 375 425 327 422C297 440 264 449 231 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Stem Cells International

tab2

Table 2

Table 2: Characterization and Study of Gene Expression Profiles of Human Periodontal Mesenchymal Stem Cells in Spheroid Cultures by Transcriptome Analysis 

Table 2 | Characterization and Study of Gene Expression Profiles of Human Periodontal Mesenchymal Stem Cells in Spheroid Cultures by Transcriptome Analysis 