Hydrostatic Pressure Modulates Intervertebral Disc Cell Survival and Extracellular Matrix Homeostasis via Regulating Hippo-YAP/TAZ Pathway

<div>Differential expression of N-CDH and integrin <i>β</i>1 in the rabbit notochordal NP and fibrocartilaginous inner AF: (a) N-CDH (red) and integrin <i>β</i>1 (green) fluorescent staining of rabbit notochordal NP (200x); (b) statistic analysis of fluorescent N-CDH AOD value of the notochordal NP and fibrocartilaginous inner AF; (c) N-CDH (red) and integrin <i>β</i>1 (green) fluorescent staining of rabbit fibrocartilaginous inner AF (200x); (d) statistic analysis of fluorescent integrin <i>β</i>1 AOD value of the notochordal NP and fibrocartilaginous inner AF. <span class="nowrap"><svg height="10.7395pt" id="M22" style="vertical-align:-0.6370001pt" version="1.1" viewbox="-0.0498162 -10.1025 50.9184 10.7395" width="50.9184pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0091,0,0,-0.0091,0,-5.741)"><path d="M486 158C486 177 478 202 466 220C413 228 386 236 336 262C386 288 413 297 466 304C478 323 486 347 485 366C470 376 444 381 422 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Stem Cells International

fig6

Figure 6

Figure 6: Hydrostatic Pressure Modulates Intervertebral Disc Cell Survival and Extracellular Matrix Homeostasis via Regulating Hippo-YAP/TAZ Pathway 