TAB2 Promotes the Stemness and Biological Functions of Cervical Squamous Cell Carcinoma Cells

Figure 4

TAB2 knockdown inhibits the stemness of cervical cancer cells. (a) Protein levels of SOX2 and BMI1 were detected by Western blot after knockdown of TAB2 in Siha cells. (b) Protein levels of SOX2 and BMI1 were detected by Western blot after knockdown of TAB2 in MS751 cells. (c) TAB2 knockdown inhibited the sphere formation efficiency in Siha and MS751 cells. (d) TAB2 knockdown inhibited the capacity of sphere formation in Siha cells. (e) TAB2 knockdown inhibited the capacity of sphere formation in MS751 cells. (f) ALDEFLUOR kit was used to assess the proportion of ALDH^br in Siha cells intervened with TAB2 or not. (g) The ability of stemness maintenance in MS751 cells was assessed by ALDEFLUOR kit.

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