Exosomes from Kartogenin-Pretreated Infrapatellar Fat Pad Mesenchymal Stem Cells Enhance Chondrocyte Anabolism and Articular Cartilage Regeneration

Table 1

International Cartilage Repair Society macroscopic evaluation of cartilage repair.

Categories	Score
Degree of defect repair
In level with surrounding cartilage	4
75% repair of defect depth	3
50% repair of defect depth	2
25% repair of defect depth	1
No repair of defect depth	0
Integration to border zone
Complete integration with surrounding cartilage	4
Demarcation	3
Three-quarters of graft integrated, one-quarter with a notable in width	2
One-half of graft integrated with surrounding cartilage, one-half with a notable	1
From no contact to one-quarter of graft integrated with surrounding cartilage	0
Macroscopic appearance
Intact smooth surface	4
Fibrillated surface	3
Small, scattered fissures or cracks	2
Several small or few large fissures	1
Total degeneration of grafted area	0
Overall repair assessment
Grade I: normal	12
Grade II: nearly normal	8–11
Grade III: abnormal	4–7
Grade IV: severely abnormal	0–3