Semaphorin3B Promotes Proliferation and Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells in a High-Glucose Microenvironment

<div>Effects of Sema3B on BMSCs by the Akt pathway under HG treatment. (a) Representative western blots are shown. (b) The expression levels of phospho-Akt and Akt were evaluated by western blotting. (c) ALP activity of BMSCs was detected using an ALP activity detection kit. (d) BMSC proliferation was assessed by CCK-8 assay. Cells were pretreated with an Akt inhibitor (MK2206) (10 <i>μ</i>M) for 2 h followed by stimulation with HG or HG + Sema3B. Then, (e) ALP activity of BMSCs and (f) the proliferation of BMSCs were assessed. 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Stem Cells International

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Figure 6

Figure 6: Semaphorin3B Promotes Proliferation and Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells in a High-Glucose Microenvironment 

Figure 6 | Semaphorin3B Promotes Proliferation and Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells in a High-Glucose Microenvironment 